sandaretreats

Hunger Hormones make you fat!

9509fd7d-930a-48c1-a413-61b45ef7b9a1Why can’t an alcoholic stop drinking?  Why can’t a smoker stop smoking?

It’s the same with an overweight to reduce weight as the person is always hungry and wanting food.

Constant craving

Marilyn Walsh, a 38-year-old housewife from London, was unsuccessful to reduce her weight through dieting.

What is different about people like Marilyn?

Dr Carel Le Roux, of Imperial College and King’s College Hospital in London, studies obesity and the underlying processes that help control the decisions you all make to eat or overeat and found that the gut can actually talk to the brain and influence how hungry you are, or how full you are.

In 2001, the research unit at Imperial discovered two previously unknown hormones called PYY and ghrelin which seem to play a part in your sensations of fullness and hunger. Ghrelin was linked to the sensation of hunger and PYY to fullness.

For many obese patients, concentrations of hunger hormones are in many cases significantly different from those in thin people.  Their PYY tells them when to stop eating, is not working properly. Instead their hormones are making them feel permanently hungry – just as Marilyn had described.

Drastic intervention

Last October, Marilyn was admitted to King’s College Hospital to undergo a stomach bypass operation. The surgery involved cutting her stomach in two, and connecting only the smaller part to her small intestines. Effectively her stomach was reduced from the size of a fist to the size of a thumb. After the surgery, she was never able to eat a full meal again, profoundly affecting her weight.

According to research by Dr Le Roux, such operation has a powerful and unexpected side-effect. While reducing her stomach, the operation also re-balanced her hormones. And for the first time in her life, Marilyn stopped thinking like a fat person and behave like a slim one.

Brain activity

A few weeks after her operation, Marilyn had lost more than four stone (earlier 21 stone). Significantly her taste had changed.

Psychiatrist Dr Samantha Scholtz has been researching how the brain responds to different kinds of food. Stimulated areas of the brain include the orbital frontal cortex, associated with reward, and other areas associated with addiction and an emotional response to food.

The patients who had undergone gastric bypass surgery had their brain activity totally changed. Their reaction to seeing high-calorie food is different, and that would ultimately drive their choices of food, so that they stop having that battle with food. You can put things into the bowel or you can use injections or pills that actually will do what the operations are achieving. Now if you do that, it opens up the whole science of obesity.

463 thoughts on “Hunger Hormones make you fat!”

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  126. {Tôi cực kỳ hài lòng khám phá trang web này. Tôi muốn cảm ơn bạn {vì đã|dành thời gian cho|chỉ vì điều này|vì điều này|cho bài đọc tuyệt vời này!! Tôi chắc chắn yêu thích từng một phần nó và tôi đã đánh dấu để xem thông tin mới trên blog của bạn.|Tôi có thể chỉ nói rằng thật nhẹ nhõm để khám phá một người thực sự hiểu họ là gì thảo luận trên web. Bạn chắc chắn biết cách đưa một rắc rối ra ánh sáng và làm cho nó trở nên quan trọng. Nhiều người hơn cần phải xem điều này và hiểu khía cạnh này của. Thật ngạc nhiên bạn không nổi tiếng hơn cho rằng bạn chắc chắn nhất có món quà.|Tốt bài đăng. Tôi hoàn toàn đánh giá cao trang web này. Tiếp tục làm tốt!|Thật khó tìm những người có hiểu biết sâu rộng trong chủ đề cụ thể này, nhưng bạn có vẻ bạn biết mình đang nói gì! Cảm ơn|Bạn nên tham gia một cuộc thi dành cho một blog trên mạng tuyệt vời nhất. Tôi sẽ khuyến nghị trang web này!|Một cuộc thảo luận thú vị đáng giá bình luận. Tôi tin rằng bạn cần xuất bản thêm về chủ đề này, nó có thể không là một điều cấm kỵ vấn đề nhưng thường xuyên mọi người không thảo luận vấn đề những điều này. Đến phần tiếp theo! Trân trọng!|Xin chào! Tôi chỉ muốn cho bạn một rất to cho thông tin xuất sắc bạn có ở đây trên bài đăng này. Tôi đang quay lại blog của bạn để biết thêm thông tin sớm nhất.|Khi tôi ban đầu để lại bình luận tôi có vẻ như đã nhấp vào hộp kiểm -Thông báo cho tôi khi có bình luận mới- và bây giờ mỗi lần được thêm vào tôi nhận được 4 email cùng chính xác một bình luận. Phải có một cách bạn có thể xóa tôi khỏi dịch vụ đó không? Kudos.|Lần sau Tôi đọc một blog, Tôi hy vọng rằng nó sẽ không thất bại nhiều như bài này. Ý tôi là, Tôi biết điều đó là sự lựa chọn của tôi để đọc hết, dù sao thì tôi thực sự nghĩ bạn sẽ có điều gì đó hữu ích để nói về. Tất cả những gì tôi nghe được là một loạt phàn nàn về điều gì đó mà bạn có thể sửa nếu bạn không quá bận tìm kiếm sự chú ý.|Đúng với bài viết này, tôi thực sự tin trang web này cần nhiều hơn nữa sự chú ý.

  127. {Tôi đã cực kỳ hài lòng khám phá trang web tuyệt vời này. Tôi muốn cảm ơn bạn {vì đã|dành thời gian cho|chỉ vì điều này|vì điều này|cho bài đọc tuyệt vời này!! Tôi chắc chắn thực sự thích từng một chút nó và tôi đã lưu làm mục ưa thích để xem điều mới trong blog của bạn.|Tôi có thể chỉ nói rằng thật nhẹ nhõm để khám phá một người mà thực sự biết họ là gì thảo luận trên internet. Bạn chắc chắn hiểu cách đưa một vấn đề ra ánh sáng và làm cho nó trở nên quan trọng. Nhiều người hơn nữa phải đọc điều này và hiểu khía cạnh này của. Tôi không thể tin bạn không nổi tiếng hơn vì bạn chắc chắn có món quà.|Rất tốt bài đăng. Tôi chắc chắn yêu thích trang web này. Tiếp tục với nó!|Thật khó tìm những người có kinh nghiệm về điều này, tuy nhiên, bạn có vẻ bạn biết mình đang nói gì! Cảm ơn|Bạn nên là một phần của một cuộc thi dành cho một blog trực tuyến hữu ích nhất. Tôi chắc chắn sẽ khuyến nghị trang web này!|Một hấp dẫn đáng giá bình luận. Tôi tin rằng bạn nên xuất bản thêm về vấn đề này, nó có thể không là một điều cấm kỵ chủ đề nhưng điển hình mọi người không thảo luận vấn đề như vậy. Đến phần tiếp theo! Chúc mọi điều tốt đẹp nhất!|Chào buổi sáng! Tôi chỉ muốn đề nghị rất cho thông tin tuyệt vời bạn có ngay tại đây trên bài đăng này. Tôi đang quay lại trang web của bạn để biết thêm thông tin sớm nhất.|Sau khi tôi ban đầu bình luận tôi có vẻ như đã nhấp vào hộp kiểm -Thông báo cho tôi khi có bình luận mới- và từ bây giờ mỗi lần được thêm vào tôi nhận được 4 email có cùng nội dung. Có một cách bạn có thể xóa tôi khỏi dịch vụ đó không? Chúc mừng.|Lần sau Tôi đọc một blog, Tôi hy vọng rằng nó không thất bại nhiều như bài này. Rốt cuộc, Tôi biết điều đó là sự lựa chọn của tôi để đọc, nhưng tôi thực sự nghĩ bạn sẽ có điều gì đó hữu ích để nói. Tất cả những gì tôi nghe được là một loạt khóc lóc về điều gì đó mà bạn có thể sửa nếu bạn không quá bận tìm kiếm sự chú ý.|Đúng với bài viết này, tôi hoàn toàn tin rằng trang web này cần nhiều hơn nữa sự chú ý.

  128. {Tôi khá hài lòng khám phá trang web tuyệt vời này. Tôi muốn cảm ơn bạn {vì đã|dành thời gian cho|chỉ vì điều này|vì điều này|cho bài đọc tuyệt vời này!! Tôi chắc chắn thực sự thích từng một phần nó và tôi đã đã lưu vào mục ưa thích để xem những thứ mới trên trang web của bạn.|Tôi có thể chỉ nói rằng thật nhẹ nhõm để tìm thấy một người mà thực sự hiểu họ là gì thảo luận trên web. Bạn chắc chắn hiểu cách đưa một vấn đề ra ánh sáng và làm cho nó trở nên quan trọng. Nhiều người hơn cần phải kiểm tra điều này và hiểu khía cạnh này câu chuyện của bạn. Tôi đã ngạc nhiên rằng bạn không nổi tiếng hơn vì bạn chắc chắn có món quà.|Tốt bài đăng. Tôi chắc chắn đánh giá cao trang web này. Tiếp tục làm tốt!|Thật khó tìm những người có học thức về điều này, nhưng bạn nghe có vẻ bạn biết mình đang nói gì! Cảm ơn|Bạn cần là một phần của một cuộc thi dành cho một trang web trên web tốt nhất. Tôi sẽ khuyến nghị trang web này!|Một động lực chắc chắn đáng giá bình luận. Không còn nghi ngờ gì nữa rằng bạn nên viết thêm về chủ đề này, nó có thể không là một điều cấm kỵ vấn đề nhưng điển hình mọi người không nói về những chủ đề những điều này. Đến phần tiếp theo! Cảm ơn rất nhiều.|Chào buổi sáng! Tôi chỉ muốn đề nghị rất cho thông tin xuất sắc bạn có ở đây trên bài đăng này. Tôi sẽ là quay lại trang web của bạn để biết thêm thông tin sớm nhất.|Khi tôi ban đầu để lại bình luận tôi có vẻ như đã nhấp hộp kiểm -Thông báo cho tôi khi có bình luận mới- và từ bây giờ mỗi lần được thêm vào tôi nhận được bốn email có cùng nội dung. Phải có một phương pháp dễ dàng bạn có thể xóa tôi khỏi dịch vụ đó không? Kudos.|Lần sau Tôi đọc một blog, Hy vọng rằng nó không làm tôi thất vọng nhiều như bài này. Rốt cuộc, Tôi biết điều đó là sự lựa chọn của tôi để đọc hết, nhưng tôi thực sự nghĩ bạn sẽ có điều gì đó hữu ích để nói về. Tất cả những gì tôi nghe được là một loạt phàn nàn về điều gì đó mà bạn có thể sửa nếu bạn không quá bận tìm kiếm sự chú ý.|Đúng với bài viết này, tôi thành thật nghĩ trang web tuyệt vời này cần nhiều hơn nữa sự chú ý.

  129. {Tôi rất vui khám phá trang web này. Tôi muốn cảm ơn bạn {vì đã|dành thời gian cho|chỉ vì điều này|vì điều này|cho bài đọc tuyệt vời này!! Tôi chắc chắn yêu thích từng của nó và tôi cũng đã đã đánh dấu trang để xem thông tin mới trong trang web của bạn.|Tôi có thể chỉ nói rằng thật thoải mái để khám phá một người thực sự biết họ là gì thảo luận trên internet. Bạn chắc chắn hiểu cách đưa một vấn đề ra ánh sáng và làm cho nó trở nên quan trọng. Nhiều người hơn nữa phải đọc điều này và hiểu khía cạnh này câu chuyện của bạn. Tôi đã ngạc nhiên rằng bạn không nổi tiếng hơn cho rằng bạn chắc chắn sở hữu món quà.|Rất tốt bài viết. Tôi chắc chắn yêu thích trang web này. Tiếp tục viết!|Thật khó tìm những người có kinh nghiệm trong chủ đề cụ thể này, tuy nhiên, bạn có vẻ bạn biết mình đang nói gì! Cảm ơn|Bạn nên là một phần của một cuộc thi dành cho một trang web trên mạng tuyệt vời nhất. Tôi chắc chắn sẽ Rất khuyến nghị trang web này!|Một hấp dẫn đáng giá bình luận. Tôi tin rằng bạn nên xuất bản thêm về vấn đề này, nó có thể không là một điều cấm kỵ vấn đề nhưng thường xuyên mọi người không thảo luận những chủ đề như vậy. Đến phần tiếp theo! Trân trọng!|Xin chào! Tôi chỉ muốn đề nghị rất cho thông tin tuyệt vời bạn có ở đây trên bài đăng này. Tôi đang quay lại trang web của bạn để biết thêm thông tin sớm nhất.|Sau khi tôi ban đầu để lại bình luận tôi có vẻ như đã nhấp hộp kiểm -Thông báo cho tôi khi có bình luận mới- và từ bây giờ bất cứ khi nào có bình luận được thêm vào tôi nhận được 4 email cùng chính xác một bình luận. Phải có một phương pháp dễ dàng bạn có thể xóa tôi khỏi dịch vụ đó không? Cảm ơn rất nhiều.|Lần sau nữa Tôi đọc một blog, Tôi hy vọng rằng nó không thất bại nhiều như bài này. Rốt cuộc, Vâng, đó là sự lựa chọn của tôi để đọc hết, tuy nhiên tôi thực sự nghĩ có lẽ có điều gì đó thú vị để nói về. Tất cả những gì tôi nghe được là một loạt khóc lóc về điều gì đó mà bạn có thể sửa nếu bạn không quá bận tìm kiếm sự chú ý.|Đúng với bài viết này, tôi thực sự tin trang web này cần nhiều hơn nữa sự chú ý.

  130. {Tôi đã rất hài lòng khám phá trang web tuyệt vời này. Tôi cần cảm ơn bạn {vì đã|dành thời gian cho|chỉ vì điều này|vì điều này|cho bài đọc tuyệt vời này!! Tôi chắc chắn thích thú từng của nó và tôi đã đã đánh dấu trang để xem điều mới trong blog của bạn.|Tôi có thể chỉ nói rằng thật nhẹ nhõm để khám phá một cá nhân mà thực sự biết họ là gì thảo luận trên mạng. Bạn chắc chắn biết cách đưa một rắc rối ra ánh sáng và làm cho nó trở nên quan trọng. Nhiều người hơn cần xem điều này và hiểu khía cạnh này câu chuyện của bạn. Tôi không thể tin bạn không nổi tiếng hơn vì bạn chắc chắn sở hữu món quà.|Rất hay bài viết trên blog. Tôi chắc chắn yêu thích trang web này. Tiếp tục viết!|Thật gần như không thể tìm thấy những người có kinh nghiệm trong chủ đề cụ thể này, nhưng bạn có vẻ bạn biết mình đang nói gì! Cảm ơn|Bạn nên là một phần của một cuộc thi dành cho một blog trực tuyến có chất lượng cao nhất. Tôi sẽ Rất khuyến nghị trang web này!|Một hấp dẫn chắc chắn đáng giá bình luận. Không còn nghi ngờ gì nữa rằng bạn nên viết thêm về chủ đề này, nó có thể không là một điều cấm kỵ chủ đề nhưng thường xuyên mọi người không nói về chủ đề những điều này. Đến phần tiếp theo! Trân trọng.|Xin chào! Tôi chỉ muốn cho bạn một rất cho thông tin xuất sắc bạn có ngay tại đây trên bài đăng này. Tôi sẽ là quay lại trang web của bạn để biết thêm thông tin sớm nhất.|Khi tôi ban đầu để lại bình luận tôi có vẻ như đã nhấp hộp kiểm -Thông báo cho tôi khi có bình luận mới- và từ bây giờ mỗi lần được thêm vào tôi nhận được 4 email cùng chính xác một bình luận. Có một cách bạn có thể xóa tôi khỏi dịch vụ đó không? Chúc mừng.|Lần sau nữa Tôi đọc một blog, Tôi hy vọng rằng nó không thất bại nhiều như bài này. Rốt cuộc, Vâng, đó là sự lựa chọn của tôi để đọc hết, tuy nhiên tôi thực sự nghĩ bạn sẽ có điều gì đó hữu ích để nói về. Tất cả những gì tôi nghe được là một loạt rên rỉ về điều gì đó mà bạn có thể sửa nếu bạn không quá bận tìm kiếm sự chú ý.|Đúng với bài viết này, tôi hoàn toàn cảm thấy trang web tuyệt vời này cần nhiều hơn nữa sự chú ý.

  131. {Tôi đã rất vui khám phá trang web tuyệt vời này. Tôi cần cảm ơn bạn {vì đã|dành thời gian cho|chỉ vì điều này|vì điều này|cho bài đọc tuyệt vời này!! Tôi chắc chắn thưởng thức từng một phần nó và tôi đã đánh dấu để xem những thứ mới trong trang web của bạn.|Tôi có thể chỉ nói rằng thật nhẹ nhõm để khám phá một người thực sự biết họ là gì đang nói về trên internet. Bạn chắc chắn hiểu cách đưa một vấn đề ra ánh sáng và làm cho nó trở nên quan trọng. Nhiều người hơn nữa cần đọc điều này và hiểu khía cạnh này của. Thật ngạc nhiên bạn không nổi tiếng hơn cho rằng bạn chắc chắn nhất sở hữu món quà.|Rất hay bài viết. Tôi chắc chắn đánh giá cao trang web này. Cảm ơn!|Thật gần như không thể tìm thấy những người hiểu biết về điều này, tuy nhiên, bạn nghe có vẻ bạn biết mình đang nói gì! Cảm ơn|Bạn nên tham gia một cuộc thi dành cho một trang web trực tuyến có chất lượng cao nhất. Tôi sẽ Rất khuyến nghị blog này!|Một hấp dẫn chắc chắn đáng giá bình luận. Tôi tin rằng bạn nên xuất bản thêm về chủ đề này, nó có thể không là một điều cấm kỵ vấn đề nhưng thường xuyên mọi người không nói về chủ đề như vậy. Đến phần tiếp theo! Trân trọng.|Chào buổi sáng! Tôi chỉ muốn đề nghị rất to cho thông tin tuyệt vời bạn có ở đây trên bài đăng này. Tôi đang trở lại trang web của bạn để biết thêm thông tin sớm nhất.|Sau khi tôi ban đầu để lại bình luận tôi có vẻ như đã nhấp hộp kiểm -Thông báo cho tôi khi có bình luận mới- và từ bây giờ mỗi lần được thêm vào tôi nhận được bốn email có cùng nội dung. Có lẽ có một phương tiện bạn có thể xóa tôi khỏi dịch vụ đó không? Cảm kích.|Lần sau nữa Tôi đọc một blog, Tôi hy vọng rằng nó sẽ không làm tôi thất vọng nhiều như bài này. Rốt cuộc, Tôi biết điều đó là sự lựa chọn của tôi để đọc, dù sao thì tôi thực sự nghĩ bạn sẽ có điều gì đó thú vị để nói về. Tất cả những gì tôi nghe được là một loạt tiếng rên rỉ về điều gì đó mà bạn có thể sửa nếu bạn không quá bận tìm kiếm sự chú ý.|Đúng với bài viết này, tôi thực sự tin trang web này cần nhiều hơn nữa sự chú ý.

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