sandaretreats

Spice drug – relief to stroke damage!

9a5784ce-e0ff-4187-89b7-535aca17bb04A drug derived from the curry spice turmeric may be able to help the body repair some of the damage caused in the immediate aftermath of a stroke.

 Turmeric has been used for centuries as part of traditional Indian Ayurvedic medicine, and many laboratory studies suggest one of its components, curcumin, might have various beneficial properties.  However, curcumin cannot pass the “blood brain barrier” which protects the brain from potentially toxic molecules.

When brain tissue is deprived of blood and oxygen, a cascading series of interrelated events triggers at the molecular level, breaking down the normal electrical and chemical “signaling pathways” responsible for nourishing and supporting neurons. The environment quickly becomes toxic, killing brain cells and destroying their support structures.

Researchers at Cedars-Sinai Medical Center in Los Angeles are preparing to embark on human trials after promising results in rabbits.  Their drug reached brain cells and reduced muscle and movement problems.

The Stroke Association said it was the “first significant research” suggesting that the compound could aid stroke patients.

The US researchers, who reported their results to a stroke conference, modified curcumin to come up with a new version, CNB-001, which could pass the blood brain barrier.  The laboratory tests on rabbits suggested it might be effective up to three hours after a stroke in humans – about the same time window available for current “clot-busting” drugs.

Chain reaction:

Dr Paul Lapchak, who led the study, said that the drug appeared to have an effect on “several critical mechanisms” which might keep brain cells alive after a stroke.  Although strokes kill brain cells by depriving them of oxygenated blood, this triggers a chain reaction which can widen the damaged area – and increase the level of disability suffered by the patient.

Dr Lapchak said that CNB-001 appeared to repair four “signalling pathways” which are known to help fuel the runaway destruction of brain cells.  Though human trials are being planned, any new treatment could still be some time away.

Dr Sharlin Ahmed, from The Stroke Association, said that turmeric was known to have health benefits.   She said: “There is a great need for new treatments which can protect brain cells after a stroke and improve recovery.”

This is the first significant research to show that turmeric could be beneficial to stroke patients by encouraging new cells to grow and preventing cell death after a stroke.  The results look promising, however it is still very early days and human trials need to be undertaken.

99 thoughts on “Spice drug – relief to stroke damage!”

  1. Wow, amazing weblog format! How long have you ever been running a blog for?

    you made blogging glance easy. The total glance of your web site is fantastic, as
    smartly as the content material! You can see similar here ecommerce

  2. Hey! Do you know if they make any plugins to assist with Search Engine Optimization?
    I’m trying to get my website to rank for some targeted keywords but I’m not seeing very good success.
    If you know of any please share. Cheers!
    I saw similar text here: Auto Approve List

  3. Hello there! Do you know if they make any plugins to
    assist with Search Engine Optimization? I’m trying to
    get my website to rank for some targeted keywords but I’m not seeing very good gains.
    If you know of any please share. Thanks! I saw
    similar blog here: Which escape room

  4. I’ve been browsing online greater than 3 hours nowadays, yet I never found any interesting article like yours. It is lovely price enough for me. In my view, if all web owners and bloggers made just right content as you probably did, the net will be much more useful than ever before!

  5. Everything is very open with a precise clarification of the challenges. It was truly informative. Your site is extremely helpful. Thank you for sharing.

  6. Hi! Do you know if they make any plugins to help with SEO?
    I’m trying to get my site to rank for some targeted
    keywords but I’m not seeing very good results. If you know of
    any please share. Cheers! You can read similar text here

  7. Hello, There’s no doubt that your web site may be having browser compatibility issues. Whenever I take a look at your website in Safari, it looks fine however, when opening in IE, it’s got some overlapping issues. I simply wanted to provide you with a quick heads up! Besides that, fantastic website.

  8. Next time I read a blog, Hopefully it doesn’t fail me just as much as this one. After all, Yes, it was my choice to read, but I actually thought you would probably have something interesting to talk about. All I hear is a bunch of complaining about something you can fix if you weren’t too busy looking for attention.

  9. Hello. Cool article. There is an issue with your web site in internet explorer, and you might want to check this… The browser is the marketplace chief and a big section of people will omit your great writing because of this problem.

  10. An interesting discussion is definitely worth comment. I think that you need to write more about this subject, it may not be a taboo matter but generally people don’t discuss such issues. To the next! Many thanks.

  11. Hoping to go into business venture world-wide-web Indicates revealing your products or services furthermore companies not only to ladies locally, but nevertheless , to many prospective clients in which are online in most cases. e-wallet

  12. You’re so interesting! I don’t suppose I have read through something like this before. So great to discover another person with genuine thoughts on this subject. Really.. thanks for starting this up. This website is something that is required on the internet, someone with some originality.

  13. I am often to running a blog and i actually appreciate your content. The article has actually peaks my interest. I am going to bookmark your site and preserve checking for brand new information.

  14. Hello, I think your blog may be having web browser compatibility issues. Whenever I look at your blog in Safari, it looks fine but when opening in IE, it’s got some overlapping issues. I merely wanted to give you a quick heads up! Other than that, fantastic blog!

  15. You can definitely see your skills in the work you write. The world hopes for more passionate writers like you who are not afraid to mention how they believe. At all times follow your heart.

  16. Hello Dear, What you ?came up with here surely have me excited up to the last sentence, and I gotta tell you I almost never read through the entire post of blogs as I often got bored and tired of the junk that is presented in the junkyard of the world wide web on a daily basis and then I just end up checking out the headlines and maybe the first lines or something like that. But your tag-line and the first paragraphs were so cool and it immediately grabbed my attention. So, I just wanna say: nice and rare job! Thanks, really.

  17. I am glad for writing to let you know what a impressive encounter my child had reading through the blog. She learned such a lot of details, not to mention what it’s like to possess an excellent giving mood to make folks with ease know several tricky issues. You actually surpassed visitors’ desires. Thanks for supplying the powerful, safe, explanatory and even cool tips on your topic to Ethel.

  18. Mention the year together with your key words as on-line end users are ecstatic to have most recent info. This is a great way of finding blog page commenting. Your blog or weblogs will need to appearance appealing, eye-catching plus the title have to be unique to ensure viewers cannot resist looking through it.

  19. Chaga mushroom dinner might have been taught a lot of globally by means of Euro contributor Alexandr Solzhenitsyn michael’s narrative ‘Cancer Ward’ exactly where the large person could alleviated linked with types of cancer among help from this specific coffee. Chaga Mushroom

  20. I in addition to my buddies happened to be going through the excellent guides located on the website then unexpectedly I got a horrible suspicion I never thanked you for those tips. All of the guys happened to be stimulated to study them and already have unquestionably been using them. I appreciate you for really being really kind and then for deciding upon these kinds of nice tips most people are really wanting to be informed on. Our sincere regret for not expressing gratitude to sooner.

  21. I feel that is one from the most significant info for me. And i am glad examining your write-up. But wish to remark on few general points, The web-site style is great, the articles or blog posts is genuinely wonderful : D. Beneficial job, cheers

  22. Very nice post. I just stumbled upon your weblog and wanted to say that I have truly enjoyed browsing your blog posts. After all I’ll be subscribing to your feed and I hope you write again soon!

  23. Hi there, just became aware of your blog through Google, and found that it’s truly informative. I’m going to watch out for brussels. I’ll be grateful if you continue this in future. Numerous people will be benefited from your writing. Cheers!

  24. The attractiveness of those blogging engines and CMS platforms could be the lack of limitations and ease of manipulation that makes it possible for developers to put into action prosperous content and ’skin’ the website in such a way that with really tiny work one particular would never ever discover what it is generating the website tick all devoid of limiting material and effectiveness.

  25. Good day! I could have sworn I’ve visited this blog before but after going through many of the articles I realized it’s new to me. Regardless, I’m certainly happy I found it and I’ll be book-marking it and checking back often!

  26. Having read this I believed it was very enlightening. I appreciate you finding the time and effort to put this short article together. I once again find myself personally spending way too much time both reading and posting comments. But so what, it was still worthwhile!

  27. Hi there, I believe your site may be having browser compatibility problems. Whenever I take a look at your blog in Safari, it looks fine however, when opening in Internet Explorer, it’s got some overlapping issues. I just wanted to give you a quick heads up! Apart from that, fantastic website!

  28. This is the perfect website for anyone who really wants to find out about this topic. You realize so much its almost hard to argue with you (not that I actually would want to…HaHa). You definitely put a fresh spin on a subject which has been discussed for many years. Excellent stuff, just excellent.

  29. Having read this I believed it was extremely enlightening. I appreciate you finding the time and effort to put this content together. I once again find myself spending a lot of time both reading and posting comments. But so what, it was still worthwhile.

  30. I would like to thank you for the efforts you have put in penning this site. I am hoping to check out the same high-grade content by you in the future as well. In fact, your creative writing abilities has inspired me to get my own website now 😉

  31. Great web site you’ve got here.. It’s difficult to find excellent writing like yours nowadays. I truly appreciate people like you! Take care!!

  32. Can I simply say what a comfort to uncover a person that genuinely knows what they’re discussing on the web. You actually realize how to bring an issue to light and make it important. More and more people really need to look at this and understand this side of the story. It’s surprising you’re not more popular given that you surely possess the gift.

  33. Good post. I learn something totally new and challenging on blogs I stumbleupon everyday. It’s always helpful to read through content from other authors and use something from their sites.

  34. An outstanding share! I’ve just forwarded this onto a co-worker who has been doing a little research on this. And he in fact bought me dinner simply because I found it for him… lol. So let me reword this…. Thanks for the meal!! But yeah, thanx for spending the time to talk about this topic here on your web site.

  35. After going over a number of the blog posts on your web site, I really appreciate your technique of blogging. I bookmarked it to my bookmark webpage list and will be checking back soon. Take a look at my web site too and tell me your opinion.

  36. A fascinating discussion is worth comment. I think that you should publish more about this topic, it might not be a taboo matter but usually people don’t speak about such subjects. To the next! All the best!

  37. I was pretty pleased to discover this web site. I want to to thank you for ones time just for this fantastic read!! I definitely really liked every little bit of it and i also have you book marked to look at new things in your web site.

Leave a Comment

Your email address will not be published. Required fields are marked *

Scroll to Top
?>