Some people are fatter than others even when they eat similar food because of genes that encourage fat storage, according to a new study.
Researchers at the University of Edinburgh identified a number of genes in fat tissue that may lead people to retain weight unnecessarily in the body. They hope the discovery could eventually lead to the development of medicines targeting obesity.
Researchers have uncovered new evidence suggesting factors other than genes could cause obesity, finding that genetically identical cells store widely differing amounts of fat depending on subtle variations in how cells process insulin. Learning the precise mechanism responsible for fat storage in cells could lead to methods for controlling obesity. The faster a cell processes insulin, the more fat it stores.
Scientists compared fat tissue from mice that had been selectively bred for many generations to be increasingly fat or thin, and as a result had acquired weight-related genes.
The researchers then pinpointed genes that prevented the breakdown of fat, which were more prevalent in the fat tissue of the overweight mice compared to the fat tissue of the lean mice.
Mice were then bred from one overweight parent and one lean parent. The offspring that turned out to be overweight were found to have the same active genes as the fatter parent mouse, suggesting that hereditary factors play a role in fat storage and can increase the likelihood of putting on weight.
Dr Nik Morton, a Wellcome Trust research career
development fellow at the University of Edinburgh’s Centre for Cardiovascular Science, said: “While genes controlling appetite are known to be important in determining our fatness, our study shows that genes switched on in the fat tissue itself can play a role in determining why some people tend to hang onto their fat more easily than others. While this supports the idea that genetic factors are linked to obesity, exercise and diet are still important for healthy lifestyles and can prevent most people from becoming obese.
“If we can identify the genes and proteins that are controlling how fat we get, we may be able to target them with medicines to try and target the obese or the consequences of obesity.”
The research also found that the thin mice offspring had an added protection against weight-gain. When both sets of mice were given fatty foods, the thin offspring appeared able to break down fatty tissue more easily than the heavier mice, suggesting they had inherited elusive “lean genes”.
The research was funded by the Wellcome Trust and published in the journal PLoS One.
794402 271355This internet site is my breathing in, extremely great layout and perfect content material . 236940
232774 708425Keep up the great piece of function, I read few posts on this internet internet site and I think that your web weblog is really interesting and contains lots of superb info. 86608
413079 773945You ought to join in a contest for starters of the highest quality blogs online. I will recommend this page! 27300
I really enjoy good vintage wine. Whether it’s red or white, it just elevates any
occasion. Are there any wine lovers around?
#WineTasting
Also visit my homepage; ซื้อไวน์ ยก ลัง ที่ไหน
อ่านแล้วเข้าใจง่ายดี ที่สรุปเรื่อง IQOS Thailand ไว้ดี เห็นภาพรวมทั้งหมดเลย
กำลังตัดสินใจซื้ออยู่ ขอคำแนะนำการเลือกซื้อหน่อยครับ
ขอบคุณสำหรับบทความดี ๆ ครับ
ถ้าใครกำลังมองหาบริการจัดดอกไม้งานศพ ผมแนะนำลองดูร้านที่มีผลงานจริงและรีวิวดี ๆ ครับ
My homepage Daniela
ชอบแนวคิดที่แชร์ไว้ในบทความนี้ครับ ถ้าใครกำลังมองหาร้านจัดดอกไม้งานศพ ผมแนะนำลองดูร้านที่มีผลงานจริงและรีวิวดี ๆ ครับ
Also vjsit my web blog; ร้านพวงหรีดวัดคลองเตยนอก
บทความนี้เกี่ยวกับการจัดดอกไม้งานศพมีสาระมาก
โดยส่วนตัวเพิ่งมีญาติจากไป
การเลือกพวงหรีดเลยเป็นเรื่องที่ต้องใส่ใจ
ใครที่กำลังเตรียมตัวจัดงานศพให้คนสำคัญควรอ่านจริงๆ
237973 621666quite good post, i definitely enjoy this fabulous site, persist with it 402074
618909 202902i was just surfing along and came upon your weblog. just wanted to say good job and this post genuinely helped me. 711420
ผมคิดว่า เฟอร์นิเจอร์ไม้สัก เป็นการลงทุนที่คุ้มค่า เพราะ ลายไม้ มีเอกลักษณ์และทนทาน โดยเฉพาะงานจาก ช่างไม้ ที่ใส่ใจ การอบไม้
Also visit my website – https://web.facebook.com/share/p/1CTpoxeAkf/
672844 812720Fantastic beat ! I wish to apprentice although you amend your web internet site, how can i subscribe for a blog website? The account aided me a appropriate deal. I had been a bit bit acquainted of this your broadcast provided bright clear idea 843122
284345 522794if the buffalo in my head could speak german i would not know a god damm thing. What i do know is that the language of art is out of this world. 223011
207581 291541I consider something truly particular in this website . 4114
294067 25867Right after study several with the weblog articles for your internet website now, and i also genuinely such as your strategy for blogging. I bookmarked it to my bookmark internet internet site list and are checking back soon. Pls take a appear at my internet page in addition and tell me what you believe. 848596
340322 214833Excellent read, I just passed this onto a colleague who was performing slightly research on that. And he in fact bought me lunch because I discovered it for him smile So let me rephrase that. 106119
421806 903573really like your imagination!!!! great function!! oh yeah.. cool photography too. 882753
787508 5135We offer the very best practical and most applicable solutions. All our Sydney plumbers are experienced and qualified and are able to swiftly assess your difficulty and uncover the best answer. 483425
555928 714991I really enjoyed reading this site, this really is wonderful weblog. 420388